Bio Protocol Price Prediction: BIO Rallies 39% Following Upbit Listing

Highlights:

• The Bio Protocol price has shown splendid bullish muscle, spiking 39% to $0.11. 
• This rally comes after BIO obtained the Upbit listing.
• Coinglass data shows a blast in volume and open interest as bulls eye the $0.13 resistance.

The Bio Protocol price has gained the spotlight among the trending coins today, rallying 39% to $0.1105. The technical outlook and the derivatives market also show weakening selling pressure, as the bulls regain control. This recent outlook comes following the Upbit listing. On October 20, 2025, BIO/KRW, BIO/BTC, and BIO/USDT trading pairs were introduced at Upbit, and the fresh momentum was put into the BIO market. 

신규 디지털 자산 바이오프로토콜(BIO) 거래지원 안내

✅ 지원 마켓: KRW, BTC, USDT 마켓
📅 거래지원 개시 시점 :2025-10-20 18:00 KST 예정

🔗공지 바로가기: https://t.co/UCizgFo1ZN #Upbit #BIO @BioProtocol pic.twitter.com/lGMtOegIhF

— Upbit Korea (@Official_Upbit) October 20, 2025

Bio Protocol team is interested in making their digital asset more accessible, which will enable BIO to appeal to more crypto traders. BIO derivatives data also demonstrates a rise in volume and open interest as a result of the increase in trading activity. This new exchange support has resulted in the market responding positively with a sharp rise in Bio Protocol price.

The derivatives data on BIO show great statistics that increase the popularity of the asset. The BIO derivatives trades have grown by 714.01% to $345.72 million. On the same note, the open interest in BIO contracts has increased by 150.65% to reach an interest of $70.87 million. This is an indication that there is an interest in the asset, and traders are jumping into positions in different exchanges.

Notably, the long-to-short ratio in the Bio Protocol price shows a bullish outlook as it sits at $1.058. This outlook indicates that the buyers are optimistic as they take a position in the longs. Furthermore, the latest statistics also show an overwhelming liquidation, and a 24-hour value of $661.29K. Traders are still active despite the volatility, as indicated in the long positions on Binance BIO/USDT. 

Bio Protocol Price Gears Up for a Surge in The Short Term

The chart shows the BIO/USDT pair on the 1-day time frame, with the price trading at $0.11. However, despite the price increase from the recent lows at $0.083 to $0.1105, the Bio Protocol price remains inside a falling wedge pattern. While this is a bullish reversal pattern, if a breakout doesn’t happen, the price could print lower lows.

The price of BIO currently trades below the 50 Simple Moving Average (SMA)at $0.1362, which acts as the immediate resistance. However, with the 200-day SMA acting as support around $0.0928, the bulls could build up the strength and obliterate the next resistance. 

The Relative Strength Index (RSI) is at 48.61 and facing upward. This signals that there may still be some room to move. Meanwhile, the Moving Average Convergence Divergence (MACD) is signaling a looming bullish outlook, which will only manifest when the blue MACD crosses above the orange signal. Momentum indicators show the Bio Protocol price may have another push before profit-taking kicks in.

If the Bio Protocol price fails to break above the current resistance at $0.13, it may drop to the $0.092 support, which aligns with the 200-day SMA. Below that, the BIO token could find lower support around $0.08-$0.07. Conversely, if bulls succeed in pushing the price beyond the falling wedge resistance ($0.136), then Bio Protocol price could skyrocket back to $0.20-$0.26.